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and Joseph A
"N1-methyl-pseudouridine in mRNA enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density
High purity
and in-vivo performance
5-OMe-UTP, 100mM Solution Amount/Package:0.1mL / centrifuge tube and Joseph A5 methoxy uridine 5 triphosphate (5moUTP) is a chemically modified uridine nucleotide designed for enzymatic incorporation into RNA during IVT using RNA polymerases such as T7 RNA polymerase. RNAs containing 5moU have been shown to exhibit reduced innate immune activation and altered translational properties compared with unmodified uridine. The 100 mM disodium salt solution provides 5moU in a highly soluble, ready to use form suitable for both
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