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Siglec-15 has unique molecular features compared to many other known checkpoint inhibitory ligands
Host Rat Antigen PD-1 (CD279) Synonyms Programmed cell death protein 1
is regulated by SOX9
" "Cells expressing the 68kDa transmembrane type II receptor (IL-1RII) include B cells
NRG1/Heregulin-β1 Protein, Human Proteins and Enzymes Siglec-15 has unique molecular featuresProduct Specification Species Human Synonyms NRG1 1; Pro neuregulin 1; Neuregulin 1 beta 1; NRG1 beta 1; HRG1 beta 1; EGF; NRG1; GGF; HGL; HRGA; NDF; SMDF Accession Q02297 6 Amino Acid Sequence Ser177 Glu241 Expression System CHO Molecular Weight 7 9 kDa(Reducing) Purity 95%, by SDS PAGE under reducing conditions Endotoxin <0. 1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4 Reconstitution