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TIMs are type I transmembrane glycoproteins with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk region
in addition to the spreading and motility of macrophages
It is selectively expressed by myelinating cells including Schwann cells in the peripheral nervous system (PNS) and oligodendrocytes in the central nervous system (CNS)
it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte
CTLA-4/CD152 His Tag Protein, Rat Cytokine & Cytokine Receptor TIMs are type I transmembraneProduct Specification Species Rat Synonyms CTLA4, CD152 Accession Q62859 Amino Acid Sequence Ile38 Asp161, with C terminal His Expression System HEK293 Molecular Weight 19 26kDa (Reducing) Purity 95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4. Reconstitution Reconstitute at 0. 1 1mg ml according to the size in ultrapure water after rapid centrifugation.